Low LATS2 expression is associated with poor prognosis in non-small cell lung carcinoma
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چکیده
منابع مشابه
Increased expression of microRNA-150 is associated with poor prognosis in non-small cell lung cancer.
OBJECTIVES The aim was to evaluate the clinical significance and prognostic value of tissue miR-150 expression in non-small cell lung cancer (NSCLC) patients. MATERIALS AND METHODS Quantitative real-time PCR was used to analyze the expression of miR-150. Overall survival (OS) was estimated using the Kaplan-Meier method, and the differences in survival were compared using the log-rank test. A ...
متن کاملFOXD1 expression is associated with poor prognosis in non-small cell lung cancer.
AIM Clinical microarray datasets were analyzed to search for new therapeutic targets and prognostic markers of non-small cell lung cancer (NSCLC). MATERIALS AND METHODS Microarray datasets from 90 lung cancer specimens, were analyzed with focus on the FOXD1 gene. Levels of FOXD1 mRNA were assessed in lung cancer cell lines and these levels were correlated with survival. RESULTS FOXD1-knockd...
متن کاملLow claudin-6 expression correlates with poor prognosis in patients with non-small cell lung cancer
OBJECTIVE Claudins are found in junctional complexes mediating cell adhesion and are involved in the attachment of tight junctions to the underlying cytoskeleton. Abnormal claudin-6 expression has been observed for a variety of malignant solid tumors, but the expression of claudin-6 in non-small cell lung cancer (NSCLC) has not yet been characterized. METHODS Immunohistochemistry, reverse tra...
متن کاملLow expression of FZD1 correlates with poor prognosis in non-small cell lung cancer
Purpose: Frizzled-1 (FZD1) is closely associated with development of various tumors, but its expression pattern in lung cancer tissues has not been elucidated enough, including the correlation in clinicopathological features and the prognostic significance of FZD1 of non-small cell lung cancer (NSCLC) patients. Methods: We evaluated immunohistochemical staining for FZD1 protein in 152 cases of ...
متن کاملLncRNA HMlincRNA717 is down-regulated in non-small cell lung cancer and associated with poor prognosis.
INTRODUCTION Long non coding RNAs (lncRNAs) have emerged recently as major players in tumor biology and may be used for cancer diagnosis, prognosis, and potential therapeutic targets. The lncRNA HMlincRNA717, a newly identified lncRNA, was demonstrated to be down-regulated in gastric cancer. However, little is known about its role in non small cell lung cancer (NSCLC). METHODS Expression of l...
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ژورنال
عنوان ژورنال: Polish Journal of Pathology
سال: 2019
ISSN: 1233-9687
DOI: 10.5114/pjp.2019.90395